Magnine 500 Tabs – An Antacid

Magnesium Trisilicate I.P. – 250 mg.
Dried Alum. Hydrox. Gel I.P. – 125 mg.
Extract Belladonna Dry I.P. – 5 mg.

Pharmacology:

Antacids are among the most widely used drugs. In patients with peptic ulcer the presence of acid in the stomach is in part responsible for the pain, which is a characteristic feature of the disease. This also interferes with the healing of these ulcers. If antacids are to be useful they should reduce gastric acidity and the action should spread over as long a period as possible. Both Magnesium trisilicate and Aluminium hydroxide have prolonged acid neutralising effect and are the two most satisfactory antacids.

The two salts are not absorbed and produce no systemic effect. Extract Belladonna blocks the action of the vagus nerve, decreases the secretion of acid and relieves pain by relieving the spasm.